Blar i forfatter "Islam, Rakibul"

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    • Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses 

      Islam, Rakibul; Islam, Mohammad Mirazul; Nilsson, Per H.; Mohlin, Camilla; Hagen, Kjersti Thorvaldsen; Paschalis, Eleftherios I.; Woods, Russell L.; Bhowmick, Sabuj Chandra; Dohlman, Claes H.; Espevik, Terje; Chodosh, James; Gonzalez-Andrades, Miguel; Mollnes, Tom Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-27)
      Inadequate supplies of donor corneas have evoked an escalating interest in corneal xenotransplantation. However, innate immune responses contribute significantly to the mechanism of xenograft rejection. We hypothesized that complement component C5 and TLR co-receptor CD14 inhibition would inhibit porcine cornea induced innate immune responses. Therefore, we measured cytokine release in human blood, ...

    • Cultural and socio-economic factors in health, health services and prevention for indigenous people 

      Sheikh, Mashhood Ahmed; Islam, Rakibul (Journal article; Tidsskriftartikkel, 2010)

    • Effects of gamma radiation sterilization on the structural and biological properties of decellularized corneal xenografts 

      Islam, Mohammad Mirazul; Sharifi, Roholah; Mamodaly, Shamina; Islam, Rakibul; Nahra, Daniel; Abusamra, Dina B.; Hui, Pui Chuen; Adibnia, Yashar; Goulamaly, Mehdi; Paschalis, Eleftherios I.; Cruzat, Andrea; Kong, Jing; Nilsson, Per; Argüeso, Pablo; Mollnes, Tom Eirik; Chodosh, James; Dohlman, Claes H.; Gonzalez-Andrades, Miguel (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-05)
      To address the shortcomings associated with corneal transplants, substantial efforts have been focused on developing new modalities such as xenotransplantion. Xenogeneic corneas are anatomically and biomechanically similar to the human cornea, yet their applications require prior decellularization to remove the antigenic components to avoid rejection. In the context of bringing decellularized corneas ...

    • Electron Beam Sterilization of Poly(Methyl Methacrylate)—Physicochemical and Biological Aspects 

      Sharifi, Sina; Islam, Mohammad Mirazul; Sharifi, Hannah; Islam, Rakibul; Huq, Tahmida N.; Nilsson, Per; Mollnes, Tom Eirik; Tran, Khoa D.; Patzer, Corrina; Dohlman, Claes H.; Patra, Hirak K.; Paschalis, Eleftherios I.; Gonzalez-Andrades, Miguel; Chodosh, James (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-24)
      Electron beam (E-beam) irradiation is an attractive and efficient method for sterilizing clinically implantable medical devices made of natural and/or synthetic materials such as poly(methyl methacrylate) (PMMA). As ionizing irradiation can affect the physicochemical properties of PMMA, understanding the consequences of E-beam sterilization on the intrinsic properties of PMMA is vital for clinical ...

    • Family planning knowledge and current use of contraception among the Mru indigenous women in Bangladesh: a multivariate analysis 

      Thorvaldsen, Gunnar; Islam, Rakibul (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Background: This article aims to understand the family planning (FP) knowledge and current use of contraception and its predictors among women of the Mru people – the most underprivileged indigenous community in Bangladesh. Methods: In this study, 374 currently married Mru women were interviewed and selected purposively from three upazilas (administrative subdistricts) of the Bandarban area, where ...

    • Innate Immune Invisible Ultrasmall Gold Nanoparticles - Framework for Synthesis and Evaluation 

      Zhu, Geyunjian Harry; Azharuddin, Mohammad; Islam, Rakibul; Rahmoune, Hassan; Deb, Suryyani; Kanji, Upasona; Das, Jyotirmoy; Osterrieth, Johannes; Aulakh, Parminder; Ibrahim-Hashi, Hashi; Manchanda, Raghav; Nilsson, Per; Mollnes, Tom Eirik; Bhattacharyya, Maitreyee; Islam, Mohammad Mirazul; Hinkula, Jorma; Slater, Nigel K. H.; Patra, Hirak K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-12)
      Nanomedicine is seen as a potential central player in the delivery of personalized medicine. Biocompatibility issues of nanoparticles have largely been resolved over the past decade. Despite their tremendous progress, less than 1% of applied nanosystems can hit their intended target location, such as a solid tumor, and this remains an obstacle to their full ability and potential with a high translational ...

    • Platelet-depletion of whole blood reveals that platelets potentiate the release of IL-8 from leukocytes Into plasma in a thrombin-dependent manner 

      Quach, Huy Quang; Johnson, Christina; Ekholt, Karin; Islam, Rakibul; Mollnes, Tom Eirik; Nilsson, Per (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-04)
      Objective: In a recent study, we found an elevated level of interleukin 8 (IL-8) in response to bacterial incubation in thrombin-sufficient human whole blood anticoagulated by the fibrin polymerization blocking peptide GPRP. Whether thrombin directly activated leukocytes or mediated the release via thrombin-dependent activation of platelets remains unresolved. Herein, we addressed the role of ...

    • Sputter deposition of titanium on poly(Methyl methacrylate) enhances corneal biocompatibility 

      Sharifi, Sina; Islam, Mohammad Mirazul; Sharifi, Hannah; Islam, Rakibul; Nilsson, Per; Dohlman, Claes H.; Mollnes, Tom Eirik; Paschalis, Eleftherios I.; Chodosh, James (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-23)
      Purpose: To evaluate titanium (Ti) sputtering of the poly(methyl methacrylate) (PMMA) stem of the Boston Keratoprosthesis (BK) as a method to enhance interfacial adhesion between the PMMA and the recipient corneal tissue.<p> <p>Methods: PMMA specimens were plasma treated with Ar/O<sub>2</sub> and coated with Ti using a DC magnetron sputtering instrument. The topography and hydrophilicity of the ...

    • Systemic inflammation persists the first year after mild traumatic brain injury: Results from the Prospective Trondheim Mild Traumatic Brain Injury Study 

      Chaban, Viktoriia; Clarke, Gerard; Skandsen, Toril; Islam, Rakibul; Einarsen, Cathrine Elisabeth; Vik, Anne; Damås, Jan Kristian; Mollnes, Tom Eirik; Håberg, Asta; Pischke, Soeren (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-03)
      Innate immune activation has been attributed a key role in traumatic brain injury (TBI) and successive morbidity. In mild TBI (mTBI), however, the extent and persistence of innate immune activation are unknown. We determined plasma cytokine level changes over 12 months after an mTBI in hospitalized and non-hospitalized patients compared with community controls; and examined their associations to ...

    • Tuning gelatin-based hydrogel towards bioadhesive ocular tissue engineering applications 

      Sharifi, Sina; Islam, Mohammad Mirazul; Sharifi, Hannah; Islam, Rakibul; Koza, Darrell; Reyes-Ortega, Felisa; Alba-Molina, David; Nilsson, Per; Dohlman, Claes H.; Mollnes, Tom Eirik; Chodosh, James; Gonzalez-Andrades, Miguel (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-17)
      Gelatin based adhesives have been used in the last decades in different biomedical applications due to the excellent biocompatibility, easy processability, transparency, non-toxicity, and reasonable mechanical properties to mimic the extracellular matrix (ECM). Gelatin adhesives can be easily tuned to gain different viscoelastic and mechanical properties that facilitate its ocular application. We ...